Luke Jostins : rechercher sur Z-Library

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1

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

Liu, Jimmy Z, van Sommeren, Suzanne, Huang, Hailiang, Ng, Siew C, Alberts, Rudi, Takahashi, Atsushi, Ripke, Stephan, Lee, James C, Jostins, Luke, Shah, Tejas, Abedian, Shifteh, Cheon, Jae Hee, Cho, Ju

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2015

2

Genetic Complexity of Crohn’s Disease in 2 Large Ashkenazi Jewish Families

Levine, Adam P., Pontikos, Nikolas, Schiff, Elena R., Jostins, Luke, Speed, Doug, Lovat, Laurence B., Barrett, Jeffrey C., Grasberger, Helmut, Plagnol, Vincent, Segal, Anthony W.

Journal:

Gastroenterology

Année:

2016

Langue:

english

Fichier:

PDF, 2.62 MB

english, 2016

3

Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets

Jostins, Luke, Morley, Katherine I, Barrett, Jeffrey C

Journal:

European Journal of Human Genetics

Année:

2011

Langue:

english

Fichier:

PDF, 324 KB

english, 2011

4

Defective tumor necrosis factor release from Crohn's disease macrophages in response to toll-like receptor activation: Relationship to phenotype and genome-wide association susceptibility loci

Gavin W. Sewell, Farooq Z. Rahman, Adam P. Levine, Luke Jostins, Philip J. Smith, Ann P. Walker, Stuart L. Bloom, Anthony W. Segal, Andrew M. Smith

Journal:

Inflammatory Bowel Diseases

Année:

2012

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2012

5

Reverse engineering a gene network using an asynchronous parallel evolution strategy

Luke Jostins, Johannes Jaeger

Journal:

BMC Systems Biology

Année:

2010

Langue:

english

Fichier:

PDF, 668 KB

english, 2010

6

Dispatches from the functional phase of genome biology

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 91 KB

english, 2012

7

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Jostins, Luke, Ripke, Stephan, Weersma, Rinse K., Duerr, Richard H., McGovern, Dermot P., Hui, Ken Y., Lee, James C., Philip Schumm, L., Sharma, Yashoda, Anderson, Carl A., Essers, Jonah, Mitrovic, Mi

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 393 KB

english, 2012

8

Next-generation sequencing and the era of personal Y genomes

Qasim Ayub, Luke Jostins, Yali Xue, Daniel Turner, Chris Tyler-Smith

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 163 KB

english, 2010

9

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

Liu, Jimmy Z, Almarri, Mohamed A, Gaffney, Daniel J, Mells, George F, Jostins, Luke, Cordell, Heather J, Ducker, Samantha J, Day, Darren B, Heneghan, Michael A, Neuberger, James M, Donaldson, Peter T,

Journal:

Nature Genetics

Année:

2012

Langue:

english

Fichier:

PDF, 510 KB

english, 2012

10

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Goyette, Philippe, Boucher, Gabrielle, Mallon, Dermot, Ellinghaus, Eva, Jostins, Luke, Huang, Hailiang, Ripke, Stephan, Gusareva, Elena S, Annese, Vito, Hauser, Stephen L, Oksenberg, Jorge R, Thomsen,

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2015

11

Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

Band, Gavin, Le, Quang Si, Jostins, Luke, Pirinen, Matti, Kivinen, Katja, Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bojang, Kalifa, Pinder, Margaret, Sirugo, Giorgio, Conway, David J., Nyirongo, Vysa

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2013

12

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

Cleynen, Isabelle, Boucher, Gabrielle, Jostins, Luke, Schumm, L Philip, Zeissig, Sebastian, Ahmad, Tariq, Andersen, Vibeke, Andrews, Jane M, Annese, Vito, Brand, Stephan, Brant, Steven R, Cho, Judy H,

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 751 KB

english, 2015

13

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Ellinghaus, David, Jostins, Luke, Spain, Sarah L, Cortes, Adrian, Bethune, Jörn, Han, Buhm, Park, Yu Rang, Raychaudhuri, Soumya, Pouget, Jennie G, Hübenthal, Matthias, Folseraas, Trine, Wang, Yunpeng,

Journal:

Nature Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2016

14

Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes

Jostins, Luke, McVean, Gilean

Journal:

Année:

2016

Fichier:

PDF, 148 KB

2016

15

Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes

Jostins, Luke, McVean, Gilean

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 148 KB

english, 2016

16

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Ji, Sun-Gou, Juran, Brian D, Mucha, Sören, Folseraas, Trine, Jostins, Luke, Melum, Espen, Kumasaka, Natsuhiko, Atkinson, Elizabeth J, Schlicht, Erik M, Liu, Jimmy Z, Shah, Tejas, Gutierrez-Achury, Jav

Journal:

Nature Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 493 KB

english, 2016

17

of inflammatory bowel disease

Jostins, Luke, Ripke, Stephan, Weersma, Rinse K, Duerr, Richard H, Dermot, P

Année:

2013

Langue:

english

Fichier:

PDF, 972 KB

english, 2013

18

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

Luo, Yang, de Lange, Katrina M, Jostins, Luke, Moutsianas, Loukas, Randall, Joshua, Kennedy, Nicholas A, Lamb, Christopher A, McCarthy, Shane, Ahmad, Tariq, Edwards, Cathryn, Serra, Eva Goncalves, Har

Journal:

Nature Genetics

Année:

2017

Langue:

english

Fichier:

PDF, 5.19 MB

english, 2017

19

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

de Lange, Katrina M, Moutsianas, Loukas, Lee, James C, Lamb, Christopher A, Luo, Yang, Kennedy, Nicholas A, Jostins, Luke, Rice, Daniel L, Gutierrez-Achury, Javier, Ji, Sun-Gou, Heap, Graham, Nimmo, E

Journal:

Nature Genetics

Année:

2017

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2017

20

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease

Lee, James C, Biasci, Daniele, Roberts, Rebecca, Gearry, Richard B, Mansfield, John C, Ahmad, Tariq, Prescott, Natalie J, Satsangi, Jack, Wilson, David C, Jostins, Luke, Anderson, Carl A, Traherne, Ja

Journal:

Nature Genetics

Année:

2017

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2017

21

Fine-mapping inflammatory bowel disease loci to single-variant resolution

Huang, Hailiang, Fang, Ming, Jostins, Luke, Umićević Mirkov, Maša, Boucher, Gabrielle, Anderson, Carl A., Andersen, Vibeke, Cleynen, Isabelle, Cortes, Adrian, Crins, François, D’Amato, Mauro, Deffonta

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 3.22 MB

english, 2017

22

Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank

Cortes, Adrian, Dendrou, Calliope A, Motyer, Allan, Jostins, Luke, Vukcevic, Damjan, Dilthey, Alexander, Donnelly, Peter, Leslie, Stephen, Fugger, Lars, McVean, Gil

Journal:

Nature Genetics

Année:

2017

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2017

23

Graphical Model Selection for Gaussian Conditional Random Fields in the Presence of Latent Variables

Frot, Benjamin, Jostins, Luke, McVean, Gilean

Journal:

Journal of the American Statistical Association

Année:

2018

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2018

24

Using Genetic Prediction from Known Complex Disease Loci to Guide the Design of Next-Generation Sequencing Experiments

Jostins, Luke, Levine, Adam P., Barrett, Jeffrey C., Peterlongo, Paolo

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 747 KB

english, 2013

25

Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis

von Loga, Isabell S, El-Turabi, Aadil, Jostins, Luke, Miotla-Zarebska, Jadwiga, Mackay-Alderson, Jennifer, Zeltins, Andris, Parisi, Ida, Bachmann, Martin F, Vincent, Tonia L

Journal:

Annals of the Rheumatic Diseases

Année:

2019

Fichier:

PDF, 727 KB

2019

26

Bayesian meta‐analysis across genome‐wide association studies of diverse phenotypes

Trochet, Holly, Pirinen, Matti, Band, Gavin, Jostins, Luke, McVean, Gilean, Spencer, Chris C. A.

Journal:

Genetic Epidemiology

Année:

2019

Langue:

english

Fichier:

PDF, 1013 KB

english, 2019

27

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

Glinos, Dafni A., Soskic, Blagoje, Williams, Cayman, Kennedy, Alan, Jostins, Luke, Sansom, David M., Trynka, Gosia

Journal:

Genes and Immunity

Année:

2020

Fichier:

PDF, 3.87 MB

2020